SB 218795
CAS No. 174635-53-1
SB 218795 ( —— )
Catalog No. M27703 CAS No. 174635-53-1
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 87 | Get Quote |
|
10MG | 155 | Get Quote |
|
25MG | 312 | Get Quote |
|
50MG | 507 | Get Quote |
|
100MG | 714 | Get Quote |
|
500MG | 1503 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSB 218795
-
NoteResearch use only, not for human use.
-
Brief DescriptionSB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1.
-
DescriptionSB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1.(In Vitro):SB 218795 (3-30 nM) antagonizes the contractile responses senktide-induced in a surmountable and concentration-dependent manner.(In Vivo):In rabbits, SB?218795 (0.25-1?mg/kg; i.v.) inhibits NK3 receptor-mediated pupillary constriction by maximum inhibition of 78%.
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetNeurokinin Receptor
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number174635-53-1
-
Formula Weight396.4
-
Molecular FormulaC25H20N2O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCOC(=O)[C@@H](NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Carnat A1, et al. Luteolin 7-diglucuronide, the major flavonoid compound from Aloysia triphylla and Verbena officinalis.Planta Med. 1995 Oct;61(5):490.
molnova catalog
related products
-
MDL 29,913
NK2 tachykinin receptor selective antagonist.
-
R 396
R 396 is a linear hexapeptide and is also an NK-2 tachykinin receptor antagonist.
-
L-732138
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM).